Archive : Volume - 2, Issue - 11, Month - November
1 IN VITRO EVALUATION OF ANTICANCER ACTIVITY OF GOWRI CHINTHAMANI CHENDHOORAM, SIDDHA MEDICINE AGAINST HeLa CELLS
- Mantela Durai Rajan* ,
- Velpandian Venkatachalapathy ,
- Ramalingam Shanmugam ,
- Dhanalakshmi Ganesan ,
- Pitchiahkumar Murugan ,
- Banumathi Vellaian
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Abstract : Cancer is one of the dangerous disease, modern science still struggle with this disease for complete cure without complications. The number of cancer patients’ is increasing day by day. One of the Indian traditional system of medicine, the Siddha medicinal system plays unique role in the treatment aspects of cancer. It declares enormous medicines for curing cancer. Among them Gowri Chinthamani Chendhooram (GCC) is one of the drug mentioned in classical text with anticancer potential and is also considered to be a crown of Siddha system of medicine. To explore the fruits of GCC to the world, it was underwent globally accepted technique. MTT assay for GCC was done on HeLa cell lines. Raising modern science supports the heavy metals usage in cancer treatment. At the end of this preliminary study, GCC found as a potent anticancer medicine on human cancer cells. Further studies with this medicine will pave right way towards safe and potent anticancer medicine.
Keyword : Siddha, GCC, anticancer, HeLa cells, heavy metals.
2 Comparision of Anti- Mullerian and Testosternoe Hormones in Sudanese women with PCOS at Elsir Abluehassan center for Fertility, Khartoum
- AbdElkarim A Abdrabo* ,
- Wamda Osman Abass ,
- Suhair A Ahmed
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Abstract : Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women in the reproductive age. It is characterized by an ovulation manifested as oligomenorrhea or amenorrhea, elevated levels of androgens and luteinizing hormone (LH), and polycystic ovaries by ultrasound. PCOS also encompasses a broad spectrum of clinical, hormonal and ultrasonographic characteristics.The study was aimed to compare serum AMH levels between PCOS and normal women; and to investigate the relationship between AMH and testosterone.An analytical case control study implemented in Dr. Alser Abulehassan Center for Infertility, Khartoum. A number of 50 women with PCOS and a number of 30 healthy women were recruited for the study. Medical records were examined for patients who sought fertility consultation or treatment during the period from April 2015 till June 2015. The study protocol was approved by the Medical Ethical Committee of Alneelain University. AMH and Testosterone were significantly higher in the PCOS women in comparison to normal women. The AMH was positively correlated to Testosterone (r=.691, p<0.01), and negative correlation with body excessive hair (r= - 426, p< 0.05). Also negative correlation was found between infertility and excessive body hair (r= - 3.17, p< 0.05), while no correlation was found between AMH and women age and weight. Higher serum AMH and testosterone levels in PCOS women than in healthy women; and significant positive correlations between AMH and testosterone and in the PCOS women exclusively. AMH has been proposed as a marker of PCOS and as suggested to be useful initial diagnostic test for PCOS.
Keyword : ANTI-MULLERIAN-TESTOSTERONE, PCOS, Sudanese Women
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