Abstract : Aim: To describe the methodology used to investigate the impact of blindness control activities in the southern Indian State of Andhra Pradesh. Background: The blindness control activities in Andhra Pradesh have been implemented since 1976 through the National Program for Control of Blindness (NPCB) by the Government of India through District Blindness Control Societies (DBCS). Besides Government eye care facilities, many local, national, international Non Governmental Organizations (NGOs) and private sector eye care facilities are active in controlling blindness in the state. In the year 2002 Andhra Pradesh Right to Sight Society (APRTSS) was established as part of a global initiative of VISION 2020 The Right to Sight to coordinate the efforts of various stakeholders in eye care. The present study investigated the impact of blindness control activities in the state of AP in general and with special reference to the activities of APRTSS Methods: The study was based on the six building blocks of the health care system for all the stakeholders in eye care. The baseline data for the year 2002-03 were collected from sources such as State Blindness Control Society, District Blindness Control Societies and major stakeholders in eye care in the state and also by questionnaire to managers of eye care facilities and eye care professionals. The current data are being collected for the year 2012-2013. Interviews based on Strength, Weaknesses, Opportunities and Threat (SWOT) analysis were conducted with policy makers in the Government, Managers of the eye care facilities and NGOs. Conclusion: The outcomes of the study will provide information regarding the trends in blinding eye diseases, human resources and infrastructure facilities in the last decade and information on the deficiencies in eye care service delivery that may provide the basis to formulate strategies for implementation of the VISION 2020 program in the state for coming years.      

Keyword : Methodology, Blindness, Impact, Southern Indian population, 

Abstract : A simple, precise and rapid HPLC method has been developed for the simultaneous determination of Indapamide and Perindopril in pharmaceutical dosage form. The method was carried out using Hypersil BDS C18 column (250 mm x 4.6 mm, 5µm) and mobile phase of phosphate buffer pH 3.5±0.05 and methanol in the ratio of 65:35 v/v and degassed under ultrasonication. The flow rate was 1.0 mL/min and the effluent was monitored at 215 nm. The retention times of Perindopril and Indapamide were 3.53 min and 4.09 min respectively. The method was validated. Linearity was in the range of 160 to 480 µg/mL for Perindopril and 50 to 150 µg/mL for Indapamide respectively. The percentage recoveries of both the drugs were ranging from 97.8 to 101.7 for Perindopril and 98.7 to 101.8 for Indapamide respectively from the tablet formulation. The proposed method is suitable for the routine quality control analysis of simultaneous determination of Perindopril and Indapamide in pharmaceutical dosage form.

Keyword : Perindopril, Indapamide, RP-HPLC, CI8 (4.6*250) mm, 5 micron column, Validation. Perindopril; Indapamide; RP-HPLC; Validation.

Abstract : Childhood Obesity is a major cause of mortality and morbidity around the world. Its prevalence is increasing dramatically regardless of age and geographical variation becomes a serious public health problem. A cross sectional comparative study was conducted in the Department of Biochemistry, Chittagong Medical College, Bangladesh during the period from July 2013 to June 2014. The aim of the study was to evaluate the relationship between serum lipid profile with childhood overweight and obesity. Total 100 subjects were included in this study. Among them 50 were Case (Group A) whose BMI was ≥85th percentile and 50 were Control (Group B) whose BMI (Body Mass Index) was >5th percentile to 84th percentile. Serum Total cholesterol, LDL-C (Low Density Lipoprotein Cholesterol), HDL-C(High Density Lipoprotein Cholesterol) and TG(Triglyceride) were measured in all samples in fasting state. The test statistics used to analyze the data were descriptive statistics, Chi-square (X2) test, Student’s t-Test and Correlation co-efficient. The average BMI of cases were 25.91±3.67 kg/m2 and controls were 19.12±2.10kg/m2. The mean weight of cases were 58.30±12.70 kg and controls were 46.08±8.19kg.The mean serum LDL in cases was 104.28±19.70 mg/dl and control was 77.22±19.14 mg/dl.. The mean serum TG in cases was 120.80±33.20mg/dl and control was 83.78±20.33mg/dl. In cases the mean serum HDL-C was 43.40±4.01 mg/dl and control was 45.56±4.48 mg/dl respectively. Pearson’s correlation coefficient(r) showed that there was a positive correlation between BMI and total cholesterol(r=+0.535, p=<0.005) BMI and LDL-C(r=+0.520, p=<0.005), BMI and TG (r=+0.550, p=<0.05) and negative correlation between BMI and HDL-C(r= -0.27, p=<0.005)

Keyword : Childhood obesity, Lipid profile, BMI.

Abstract : ABSTRACT Epilepsy is a chronic illness that has a great impact on the life of the epileptic children. The aim of this study was to evaluate the effect of family support program on quality of life of epileptic children. An experimental study design was used in this study. Forty five (45) epileptic children from Soba University Hospital Outpatient Clinic were selected randomly as intervention group and, another Forty five (45) epileptic children from Fathelrahaman El Basher Outpatient Clinic, selected as a control group. Data was collected on three occasions from the experimental and control group as follows: before the implementation of the program, one and 3 months after the program completion. Program activities implemented through four sessions, one hour session per week for one month. The program covered all the points evaluated by the scales, using different methods and materials such as lectures, pictures, discussion, videotapes and Hand out. Mean total quality of life significantly improved in the experimental group, at baseline data, 1 and 3 months after the program (52.85%,65.60% ,79.56%) respectively (P-value˂.0005). Unlike quality of life in control group no significant change has been observed. A significant difference in all Health related quality of life sub domains in experimental group from baseline data, 1 and 3 months after the program (p-value ˂.0005).Unlike quality of life in control group where no significant change has occurred.Conclusion: The study has shown the effectiveness of the role played by family support program in improving quality of life of epileptic children in experimental group compared to control group where no significant change has occurred.It will recommended that , educational programs must be carried out periodically for parents to provide them with proper knowledge and skills necessary for improving the quality of life for their epileptic children .

Keyword : Quality of life - Epileptic children- Family Support

Abstract : Introduction: The first permanent molars heve thebiggesth dental morbidity and mortality of all permanent teeth. The main aim was to evaluate of the most common dental problems and procedures that are performed on the first permanent molars. Material and method: examination was performed in three private dental offices, two from urban and one from rural region, over a period of 2 years.The data was obtained by using dental charts from the patients and by the ambulatory register for performed interventions. Total number of interventions of the remaining teeth was detected, which interventions are most performed and and which of the four first permanent molars have the highest morbidity. Results: on the first permanent molars were made 10.98% from the total number of interventions. 61.33 %of the subjects possessed all four first permanent molars . The left mandibular molar has the highest number of interventions performed from all first permanent molars. the most common reason for dental interventions on the first permanent molar is caries and its complications. Conclusion: In a very small number of subjects all first permanent molars were not affected by any disease. Removal of caries is the most common dental intervention on the first permanent molars.

Keyword : First molar, first permanent molar, interventions, tooth morbidity, tooth mortality

Abstract : Fever of unknown origin (FUO) is a major diagnostic challenge worldwide. Causes of FUO range from infectious diseases to malignancies and sometimes inflammatory disorders. There have been major advances made in various diagnostic fields which help in diagnosis of FUO. FDG-PET (Fluorodeoxyglucose Positron emission tomography) scans are being found helpful in diagnosing many rare causes of FUO. Here we present a rare case of FUO in which we could arrive at the diagnosis after the PET scan which showed Aorto-arteritis. Hence we concluded that PET scans may be used in diagnosing non-infectious and inflammatory causes of FUO where the preliminary investigations could not help in the diagnosis.

Keyword : – FDG-PET scan –Fluoro-deoxyglucose positron emission tomography, Aorto-arteritis, FUO- Fever of unknown origin